局部晚期非小细胞肺癌化疗同步调强适形放疗的护理分析 Influence of Nursing Intervention on Treatment Response of Concurrent Chemotherapy and Intensified Modulated Radiotherapy in Patients with Locally-advanced Non-small-cell Lung Cancer 摘要： 目的：分析护理对局部晚期非小细胞肺癌患者化疗同步调强适形放疗的近期疗效的影响。方法：选择2012年1月至2014年12月在我院接受化疗同步调强适形放疗的局部晚期非小细胞肺癌患者106例，随机将其分成观察组和对照组各53例，观察组给予针对性的护理，对照组给予常规护理，治疗后一个月应用CTCAE标准评价并比较两组患者的近期疗效，将CR、PR和SD定义为有效。结果：观察组治疗有效率高达92.4%，而对照组患者治疗有效率仅83%，观察组患者同步放化疗的近期疗效显著优于对照组，两组比较差异有统计学意义（P＜0.05）。结论：实施针对性的护理一方面融洽了患者和医务人员的关系，提升患者治疗的信心，从而使其配合治疗；同时提高了接受同步放化疗的局部晚期非小细胞肺癌患者的近期临床疗效，具有十分重要的临床意义。 Abstract： Objective:To analyze the therapeutic efficacy of nursing intervention on the treatment responses of concurrent chemotherapy and intensified modulated radiotherapy (IMRT) for patients with locally-advanced non-small-cell lung cancer (LA-NSCLC).Methods:Between Jan 2012 and Dec 2014,106 patients with LA-NSCLC who received concurrent chemotherapy and IMRT as initial treatment were randomly assigned to receive pertinent (N=53) and conventional (N=53) nursing care. Patients with complete response (CR), partial response (PR),and stable disease (SD) were defined as responders.Results:The proportion of responders to treatment in pertinent nursing care group was higher than that in conventional nursing care group (92.4%vs.83%,P<0.05). Conclusion:Pertinent nursing care during concurrent chemotherapy and IMRT could not only build harmonious relationship between patients and nurses to help patients go through the treatment but also improve the treatment responses.